Gynecologic pathology focuses on tissue-based diagnosis of neoplastic and non-neoplastic diseases of the female genital tract, including cancer. Gynecologic cancers afflict an estimated 330,000 women or more in the United States each year. If detected and diagnosed correctly and early enough, chances of patient survival rise dramatically. Therefore, it is critical for pathologists to have the skills to diagnose accurately based on testing results.

Whether refreshing or expanding their knowledge, pathologists can count on the CAP to help them stay current with ongoing diagnostic learning and other skills related to gynecologic pathology. The CAP offers several continuing medical education (CME) online courses in gynecologic pathology in a focused format. By learning on individual topics in bite-sized courses, the pathologist can spend more time on what matters – patient care.

Cervical Adenocarcinoma: from AGUS to Zebras

This online activity reviews the: 1) newly revised World Health Organization classification of endocervical adenocarcinomas based on human papilloma virus; 2) threshold criteria for distinguishing reactive changes from atypical glandular cells and adenocarcinoma in situ; and 3) 2019 ASCCP risk-based management guidelines. This activity was originally presented at CAP20 as part of the activity Cervical Adenocarcinoma: From AGUS to Zebras—Cytology and Histology of Usual Type Adenocarcinomas and Special Variants.

Course Author:

Christina S. Kong, MD
Stanford Healthcare

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HPV Infection and the LAST Guidelines

The human papilloma virus (HPV) is a main cause of malignancies in the lower anogenital tract and oropharynx. Understanding the epidemiology and life cycle of HPV helps explain the steps in HOV-related carcinogenesis. This course discusses different histopathologic features of HPV-associated precursor lesions and classifying them using the Lower Anogenital Squamous Terminology (LAST) guidelines.

Course Author:

Uma Krishnamurti, MD, PhD, FCAP
Yale School of Medicine

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Testing and Screening Guidelines for HPV

The human papilloma virus (HPV) is a main cause of malignancies in the lower anogenital tract and oropharynx. This course reviews testing for high-risk HPV infections, screening for cervical cancer using the PAP test, and key points of cytohistologic correlations in cervical pathology. In addition, it covers the American Society for Colposcopy and Cervical Pathology (ASCCP) 2019 guidelines and screenings for cervical cancer, and the current recommendations for anal and oropharyngeal cancer screening. Finally, facts and myths about the approved HPV vaccines will be discussed.

Course Author:

Krisztina Hanley, MD, FCAP
Emory Healthcare Network

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Ten Perinatal Diagnoses You Don’t Want to Miss and Why

This course focuses on placental pathologies affecting the mother and infant. It discusses what activity will identify ten perinatal diagnoses, as well as interventions to mitigate risk: chronic histiocytic intervillositis, massive perivillous fibrin deposition (maternal floor infarct), candida placentitis, CMV placentitis, maternal vascular malperfusion, massive villous edema, inborn errors of metabolism, fetal vascular malperfusion, meconium myonecrosis, and basal plate myometrial fibers.

Course Author:

Drucilla J. Roberts, MD, FCAP
Massachusetts General Hospital

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A Clinically Relevant Pattern-Based Approach to Diagnosing Uterine Mesenchymal Tumors

A pattern-based approach (spindled, epithelioid, rhabdoid, myxoid patterns; low-grade versus high-grade atypia) can build differential diagnoses and emphasize selection and interpretation of the most useful, current immunohistochemistry (IHC) and molecular tests for each diagnostic scenario of uterine mesenchymal tumors. The course highlights common pitfalls, new diagnostic tools, and features that predict response to targeted therapy; and the novel role of the pathologist in recognizing morphologic features associated with risk of a hereditary syndrome.

Course Authors:

Jennifer Bennett, MD, FCAP
University of Chicago Medical Center		Joseph Rabban, MD, MPH, FCAP
University of California San Francisco

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Benign Isn’t Boring: Daily Difficulties in Endometrial Biopsies that Go Beyond Classifying Cancer

Four key areas of benign endometrial pathology can routinely result in questions among colleagues or might prompt sending endometrial biopsies out for consultation. The course uses case studies to examine progestin treatment effects, subcarcinoma-threshold mucinous and papillary surface proliferations of the endometrium, endometrial histiocytic proliferations, and unusual endometrial polyps.

Course Authors:

Amy Joehlin-Price, MD, MS, FCAP
Cleveland Clinic

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Contact Us

If you have any questions, please contact the CAP: 800-323-4040 option #1
Email: education@cap.org