2020 CPIP-L Case 12: Immunology – Biotin Interference in Immunoassay: A Potential Cause of Diagnostic Error
Pricing: Member: $50.00 NonMember: $65.00 Junior Member: $10.00
To register for this activity, you must either pay by credit card or have ordered this product in advance. Click the Register tab then click the Enroll button, you will be prompted for validation or processed for payment.
To enroll in the series with one easy payment, or to enroll multiple participants from the same institution, call 800-323-4040 option 1. This option is only available until December 31, 2020, after this date this activity is only accessible by an online credit card payment.
Intended Audience
This clinical pathology activity is intended for pathologists.
Description
Biotin (vitamin B7) is widely used in amounts far above the recommended amount as a supplement to improve skin and hair appearance, and as a treatment for certain disorders. Because the attachment of biotin to streptavidin is often used as part of the detection system in immunoassays, large amounts of biotin in serum samples may result in erroneous results that can vary by manufacturer and assay. This activity will cover patterns of biotin interference and steps laboratories can take to minimize the effects of this interference.
Objectives
After completing this activity, you should be able to:
- Describe the usage, dosage, and pharmacokinetics of biotin.
- Recognize the impact of biotin on immunoassays.
- Explain the consequences of biotin interference from a clinical standpoint.
- Identify the possible approaches to prevent consequences of biotin interference.
Related Link
Clinical Pathology Improvement Program
CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.
College of American Pathologists
CAP Learning
325 Waukegan Road
Northfield, IL 60093-2750
Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.
Technical Requirements
Pop-up blockers must be turned off.
The CAP recognizes that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.
Availability
This activity and evaluation are available December 21, 2020 - December 20, 2023, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.
CC: CPIP1212W2.2020
Key Words: BrowseCP
Available Credit
- 1.25 AMA PRA Category 1 Credit™
- 1.25 Lifelong Learning
- 1.25 Participation
Price
Pricing: Member: $50.00 NonMember: $65.00 Junior Member: $10.00
To register for this activity, you must either pay by credit card or have ordered this product in advance. Click the Enroll button to continue, you will be prompted for validation or processed for payment.
To enroll in the series with one easy payment, or to enroll multiple participants from the same institution, call 800-323-4040 option 1. This option is only available until December 31, 2020, after this date this activity is only accessible by an online credit card payment.
Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.
College of American Pathologists
CAP Learning
325 Waukegan Road
Northfield, IL 60093-2750
Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.
Technical Requirements
Pop-up blockers must be turned off.
The CAP recognizes that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.
Availability
This activity and evaluation are available December 21, 2020 and expire December 20, 2023, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.