Pricing: Member: $60.00 NonMember: $78.00 Junior Member: $15.00

To register for this activity, you must either pay by credit card or have ordered this product in advance. Click the Register tab then click the Enroll button, you will be prompted for validation or processed for payment.

To enroll in the series with one easy payment, or to enroll multiple participants from the same institution, call 800-323-4040 option 1. This option is only available until December 31, 2026, after this date this activity is only accessible by an online credit card payment.

Intended Audience
This clinical pathology activity is intended for pathologists.

Description
In this activity, the basics of the complex molecular nomenclature system will be clarified, and some common but important molecular testing pitfalls will be explored. Learning how to accurately read and interpret a molecular testing report will strengthen the anatomic or clinical pathologist’s skills as a healthcare professional and as a consultant for clinical oncologists who are increasingly ordering next-generation sequencing testing to identify actionable biomarkers in their cancer patients.

Objectives
After completing this activity, you should be able to:

1. Interpret standard HGVS (Human Genome Variation Society) nomenclature and a tiered result interpretation system used in many molecular oncology reports.
2. Define transcript and genome versions and apply this knowledge to the interpretation of molecular reports.
3. Recognize differences in test design and apply to potential interpretation pitfalls.
4. Interpret a variant of uncertain clinical significance in the context of clinical practice.

Authors/Faculty
Jennifer M. Yoest, MD, FCAP

Related Link
Clinical Pathology Improvement Program

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
CAP Learning
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at [email protected] or fax at 847-832-8006.

Technical Requirements
Pop-up blockers must be turned off.

The CAP recognizes that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or [email protected].

Availability
This activity and evaluation are available July 20, 2026 - July 19, 2029, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.

CC: CPIP0707W.2026

Key Words: BrowseCP, Coverage Space, Clinical Actionability, Molecular Biomarker